From Molecules to Organisms High School | Students study how living things are built and how they work, from the molecules inside a single cell up to the systems that keep an entire organism alive. | HS-LS-1 |
Construct an explanation based on evidence for how the structure of DNA… High School | DNA holds the instructions for building proteins. Students learn how a cell reads those instructions, step by step, and how the proteins it builds run nearly every function in the body, from digesting food to carrying oxygen in the blood. | HS-LS-1.1 |
Develop and use a model to illustrate the hierarchical organization of… High School | Living things are organized in layers, from cells to tissues to organs to full body systems. Students build or use a model to show how each layer depends on the ones around it to keep the organism alive. | HS-LS-1.2 |
Plan and conduct an investigation to provide evidence that feedback mechanisms… High School | Students design and run an experiment to show how the body keeps conditions stable, like how sweating cools you down or how blood sugar returns to normal after a meal. | HS-LS-1.3 |
Use a model to illustrate the role of cellular division High School | Students learn how a single cell divides and specializes to build a full human body. They use diagrams or models to show how mitosis copies cells and how those copies become skin, muscle, nerve, or other tissue. | HS-LS-1.4 |
Use a model to illustrate how photosynthesis transforms light energy into… High School | Students explain how plants capture sunlight and convert it into sugar, using a diagram or model to show where the energy comes from and where it ends up. | HS-LS-1.5 |
Construct an explanation based on evidence for how carbon, hydrogen High School | Sugar molecules supply the carbon, hydrogen, and oxygen that cells rearrange, with a few added elements, to build amino acids and other large molecules the body needs. Students explain how that process works using real evidence. | HS-LS-1.6 |
Use a model to illustrate that cellular respiration is a chemical process… High School | Cellular respiration is how cells break down food and oxygen to release usable energy. Students model the chemical bond-breaking and bond-forming steps that explain why eating fuels everything from muscle movement to brain activity. | HS-LS-1.7 |
Ecosystems: Interactions, Energy High School | Students study how living things depend on each other and their environment to survive. They trace how energy moves through food webs and what happens when something in an ecosystem changes. | HS-LS-2 |
Use mathematical and/or computational representations to support explanations… High School | Students use graphs or equations to explain why a habitat can only support so many of a given species. They look at factors like food supply and space to show how those limits change at local and larger scales. | HS-LS-2.1 |
Use mathematical representations to support explanations that biotic and… High School | Students use data and graphs to explain how living things (like predators or plants) and non-living conditions (like temperature or rainfall) shape the variety of species found in an ecosystem, from a single pond to an entire region. | HS-LS-2.2 |
Construct an explanation using mathematical representations to support claims… High School | Students trace how energy moves up a food chain from plants to predators, and how matter like carbon and nitrogen cycles back through the ecosystem. They use graphs or equations to back up what they find. | HS-LS-2.3 |
Develop a model to illustrate the role of photosynthesis and cellular… High School | Plants pull carbon out of the air during photosynthesis. Students build a model showing how that carbon moves through living things, soil, water, and the atmosphere as organisms grow, eat, and break down. | HS-LS-2.4 |
Evaluate the claims, evidence High School | When conditions in an ecosystem shift, such as a drought or a new species arriving, the whole system can reorganize into something different. Students evaluate real evidence to decide whether that kind of change is likely and why. | HS-LS-2.5 |
Design, evaluate, and/or refine practices used to manage a natural resource… High School | Students look at how fishing, farming, land use, or other human activities affect local species and ecosystems, then evaluate or redesign those practices to reduce harm and keep the ecosystem functioning. | HS-LS-2.6 |
Evaluate the evidence for the role of group behavior on individual and species'… High School | Working in groups helps some animals survive and raise more offspring. Students look at real evidence to figure out when group behavior actually improves an animal's chances, and when it doesn't. | HS-LS-2.7 |
Heredity: Inheritance and Variation of Traits High School | Students study how traits pass from parents to offspring and why siblings can look different from each other. The focus is on genes, DNA, and the natural variation that shows up across generations. | HS-LS-3 |
Ask questions to clarify relationships about the role of DNA and chromosomes in… High School | DNA holds the instructions that determine a person's traits, and those instructions are packaged into chromosomes passed from parents to children. Students ask questions to understand how that process works and why offspring resemble, but don't perfectly copy, their parents. | HS-LS-3.1 |
Make and defend a claim based on evidence that inheritable genetic variations… High School | Students learn that genetic variation comes from three sources: the shuffling of genes during meiosis, copying errors in DNA, and mutations triggered by environmental exposure. They practice building an evidence-based argument for why these changes can be passed to the next generation. | HS-LS-3.2 |
Apply concepts of probability and statistical analysis to explain the variation… High School | Students use probability and basic statistics to explain why a trait like eye color or blood type shows up at different rates across a population. The math helps predict how often a trait appears, not just whether it can. | HS-LS-3.3 |
Biological Adaptation High School | Students study why living things look and behave so differently from one another, and how those differences trace back to inherited traits that helped ancestors survive. The focus is on how populations change over generations through natural selection. | HS-LS-4 |
Communicate scientific information that common ancestry and biological… High School | Students explain how fossils, DNA comparisons, and anatomical similarities across species all point to the same conclusion: living things share common ancestors and have changed over time. | HS-LS-4.1 |
Construct an explanation based on evidence that the process of evolution… High School | Students explain why populations change over time by connecting four ideas: species can multiply fast, offspring inherit genetic differences, resources run short, and the individuals best suited to their environment tend to survive and have more offspring. | HS-LS-4.2 |
Apply concepts of probability and statistical analysis to support explanations… High School | Students use probability and basic statistics to explain why a helpful inherited trait, like disease resistance or better camouflage, spreads through a population over generations while organisms without it become less common. | HS-LS-4.3 |
Construct an explanation based on evidence for how natural selection leads to… High School | Students explain, using real examples from nature, how traits that help an organism survive get passed on more often until the whole population shifts. Over generations, that process reshapes what a species looks like and how it behaves. | HS-LS-4.4 |
Evaluate models that demonstrate how changes in an environment may result in… High School | When the environment shifts, some traits help a species survive and others don't. Students examine models to see how genetic drift, gene flow, mutation, and natural selection can push a population to evolve, split into a new species, or die out entirely. | HS-LS-4.5 |